Integrated Cartilage Protection, Pain Control through Nociceptive and Neural Pathways

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How It Works

Ostizeel™ targets joint inflammation, pain pathways, and muscle weakness, offering multi-level support for cartilage protection and mobility restoration.

Clinical Evidence

Clinically proven to reduce pain and stiffness from Day 3, with validated results on WOMAC, VAS, and LFI scales.

Our Research

Developed through advanced research, Ostizeel™ combines PEA and Cucumis extract to modulate pain, inflammation, and cartilage degradation effectively.

Advanced Joint Health Support Backed by Science.

Our Approach

A clinically validated formulation targeting pain, inflammation, and cartilage degradation through integrated action on nociceptive and neuropathic pathways.

Ostizeel™ is a next-generation nutraceutical formulation designed for the comprehensive management of osteoarthritis. It combines the scientifically validated power of Palmitoylethanolamide (PEA) and Cucumis sativus extract, working synergistically to target both nociceptive and neuropathic pain pathways.

This dual-action approach delivers fast-acting relief starting from Day 3, while also addressing deeper pathological mechanisms responsible for joint inflammation, degeneration, and stiffness.

Dual Pathway Pain Modulation

Targets both nociceptive and neuropathic components of osteoarthritis for comprehensive and sustained pain relief.

Supports Muscle Strength Around Joints

Enhances peri-articular muscle function, improving joint stability and reducing stress on damaged cartilage.

Acts on Novel Molecular Targets

Interacts with mast cells, TRPV1, PPAR-α, and microglial cells to interrupt pain and inflammation at the root.

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Ostizeel™ delivers more than just pain relief

A clinical-grade solution that addresses the root causes of joint damage and offers sustainable mobility support.

Downregulates Inflammatory Biomarkers

Reduces levels of TNF-α, IL-6, NF-κB, and IL-1β, offering biological control over chronic inflammation.

Clinically Validated Outcomes

Proven efficacy in clinical trials using standard osteoarthritis metrics: WOMAC, VAS & LFI scores.

Improves Joint Function Performance

Promotes increased knee flexion strength and overall range of motion through muscle and structural support.

Superior to Conventional OA Therapies

Demonstrates better clinical outcomes compared to standard Disease-Modifying Anti-Osteoarthritis Drugs (DMOADs).

Protects and Preserves Cartilage

Inhibits matrix metalloproteinases (MMPs), preventing cartilage breakdown and supporting long-term joint integrity.

Synergistic Ingredient Composition

Combines Palmitoylethanolamide and Cucumis sativus extract for a potent, multi-targeted approach to OA care.

Research- Driven Innovation in Osteoarthritis Management

Ostizeel™ is built on robust scientific research targeting the complex pain and cartilage degradation pathways of osteoarthritis.

Multifactorial Pain Modulation

Ostizeel™ targets nociceptive and neuropathic pain by modulating mast cells, TRPV1, PPAR-α, and microglial cells, effectively interrupting pain transmission and neuroinflammation for comprehensive osteoarthritis relief.

Cartilage Preservation & Inflammation Control

The formulation inhibits matrix metalloproteinases (MMPs) and downregulates TNF-α, IL-6, NF-κB, and IL-1β, preserving cartilage integrity while reducing inflammation and slowing OA disease progression.

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